Medications

Learn about biologic treatments for allergies and asthma

Xolair (Omalizumab)

💊 Description

Xolair is a biologic medication that works by blocking immunoglobulin E (IgE), a substance in the body that can trigger allergic reactions and asthma symptoms.

Uses

  • Moderate to severe persistent asthma in patients 6 years and older with positive skin test or reactivity to a perennial aeroallergen
  • Chronic spontaneous urticaria (hives) in patients 12 years and older who remain symptomatic despite antihistamine treatment
  • Nasal polyps in adults 18 years and older with inadequate response to nasal corticosteroids

⚠️ Common Side Effects

  • Injection site reactions (pain, redness, swelling)
  • Headache
  • Joint pain
  • Upper respiratory tract infections
  • Viral infections

Nucala (Mepolizumab)

💊 Description

Nucala is a biologic medication that works by blocking interleukin-5 (IL-5), a protein that promotes the growth and survival of eosinophils, a type of white blood cell involved in allergic inflammation.

Uses

  • Severe eosinophilic asthma in patients 6 years and older
  • Chronic rhinosinusitis with nasal polyps in adults 18 years and older
  • Eosinophilic granulomatosis with polyangiitis (EGPA) in adults and children 6 years and older
  • Hypereosinophilic syndrome (HES) in adults and children 12 years and older

⚠️ Common Side Effects

  • Headache
  • Injection site reactions
  • Back pain
  • Fatigue
  • Muscle spasms
  • Upper respiratory tract infections

Tezspire (Tezepelumab)

💊 Description

Tezspire is a biologic medication that works by blocking thymic stromal lymphopoietin (TSLP), a key inflammatory molecule that sits at the top of the inflammatory cascade in asthma. It is the first and only biologic to target this specific pathway.

Uses

  • Add-on maintenance treatment for severe asthma in adults and children 12 years and older
  • Works regardless of biomarker levels (eosinophils or IgE)
  • Can be used for patients who don't respond to other biologics
  • Helps reduce asthma exacerbations and improve lung function

⚠️ Common Side Effects

  • Sore throat (pharyngitis)
  • Joint pain (arthralgia)
  • Back pain
  • Injection site reactions
  • Upper respiratory tract infections